Application of tegafur gimer, docetaxel and carboplatin in head and neck squamous cell carcinoma therapy

作者：Wang, Baoqing; Zhang, Shiqiang^*; Xue, Qingping; Xie, Yan; Ling, Guiqin; Wang, Ziquan; Chen, Xinjun

来源：Pakistan Journal of Pharmaceutical Sciences, 2016, 29(6): 2235-2238.

• Tegafur gimer
• docetaxel
• carboplatin
• head and neck squamous cell carcinoma
• clinical efficacy

Squamous cell carcinoma, in the clinical manifestation, is a form of cancer derived from lesions of keratinocytes of epidermis or accessories such as sebaceous ducts, hair follicles, sweat glands, etc. The disease is more common in older men, with prone locations at patients' scalp, face, neck and arms and other exposed parts. Head and neck squamous cell carcinoma (HNSCC) causes a serious impact on patients' daily life, making patients suffer from double blow in mental and physical aspects and reducing patients' life quality. To find effective treatment method for HNSCC, our hospital studies clinical effects of combination therapy of tegafur gimer, docetaxel and carboplatin for the disease. By way of grouping research, therapeutic effect of such treatment and adverse reactions were assessed and analyzed. The study clearly and fully confirms effectiveness of combination therapy of tegafur gimer, docetaxel and carboplatin for HNSCC.

• 出版日期2016-11
• 单位徐州医科大学