Pediatric cleft palate patients show a 3-to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study

作者：Jacobs Reinhilde^*; Pauwels Ruben; Scarfe William C.; De Cock Carl; Dula Karl; Willems Guy; Verdonck An; Politis Constantinus

来源：Clinical Oral Investigations, 2018, 22(4): 1783-1793.

DOI：10.1007/s00784-017-2274-0

• Cleft palate
• Pediatric dentistry
• Radiation protection
• Radiation dosimetry
• Radiation-induced cancer

Objective The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment.
Materials and methods The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group.
Results CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 mu Sv at the age of 20 years) than non-CP patients with (597 mu Sv) and without (383 mu Sv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients.
Conclusions This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented.

• 出版日期2018-5