MR visible localization device for radiographic-pathologic correlation of surgical specimens

作者：Kinner Sonja^*; Schubert Tilman B; Nocerino Elisabetta A; Hynes Shannon; Colgan Timothy J; Loeffler Agnes G; Brace Christopher; Reeder Scott B; Winslow Emily

来源：Magnetic Resonance Imaging, 2017, 37: 159-163.

DOI：10.1016/j.mri.2016.11.021

• Small lesions
• Detection
• Characterization
• Ex vivo

Purpose: The detection of small parenchymal hepatic lesions identified by preoperative imaging remains a challenge for traditional pathologic methods in large specimens. We developed a magnetic resonance imaging (MRI) compatible localization device for imaging of surgical specimens aimed to improve identification and localization of hepatic lesions ex vivo.
Materials and methods: The device consists of two stationary and one removable MR-visible grids lined with silicone gel, creating an orthogonal 3D matrix for lesion localization. To test the device, five specimens of swine liver with a random number of lesions created by microwave ablation were imaged on a 3 T MR scanner. Two readers independently evaluated lesion coordinates and size, which were then correlated with sectioning guided by MR imaging.
Results: All lesions (n = 38) were detected at/very close to the expected localization. Inter-reader agreement of lesion localization was almost perfect (0.92). The lesion size estimated by MRI matched macroscopic lesion size in cut specimen ( 2 mm) in 34 and 35, respectively, out of 38 lesions.
Conclusion: Use of this MR compatible device for ex vivo imaging proved feasible for detection and threedimensional localization of liver lesions, and has potential to play an important role in the ex vivo examination of surgical specimens in which pathologic correlation is clinically important.

• 出版日期2017-4