Application of the Chick Embryo Chorioallantoic Membrane in Neurosurgery Disease

作者:Yuan, Yong-Jie; Xu, Kan; Wu, Wei; Luo, Qi; Yu, Jin-Lu*
来源:International Journal of Medical Sciences, 2014, 11(12): 1275-1281.
DOI:10.7150/ijms.10443

摘要

The chick embryo chorioallantoic membrane (CAM) is a highly vascularized extraembryonic membrane. Because of its ease of accessibility, extensive vascularization and immunodeficient environment, the CAM has been broadly used in the oncology, biology, pharmacy, and tissue regeneration research. The present review summarizes the application of the CAM in neurosurgery disease research. We focused on the use of the CAM as an assay for the research of glioma, vascular anomalies, Moyamoya Disease, and the blood-brain barrier.