Antifungal activity of crude extracts and fat-soluble constituents of Holotrichia diomphalia larvae

作者：Dong, Qing-Feng; Wang, Jun-Lan; Zhang, Shu-Feng; Wang, Zhi; Zhang, Chong-Xi; Gao, He; Zhang, Han-Ming; Zhang, Lei^*

来源：Bioresource Technology, 2008, 99(17): 8521-8523.

DOI：10.1016/j.biortech.2008.03.010

• Holotrichia diomphalia larvae
• fatty oils
• petroleum ether extract
• GC/MS analysis
• supercritical fluid extraction

In this study, chemical compositions of fatty oils and bioactivity of crude extracts from Holotrichia diomphalia larvae as Chinese materia medica were investigated for the first time. The chemical compositions of the fatty oils were obtained by two different methods and determined by GC/MS. In total, the petroleum ether extract produced 21 compounds (96.3%) while the supercritical fluid extract produced six compounds (99.53%) for identification. @@@ The effect of petroleum ether and other crude extracts on Pyricularia oryzae was also examined. Results indicated that ethanol and petroleum ether extracts had excellent antifungal activities. These findings demonstrated that fatty oils from H. diomphalia larvae had great potential to be used as a source for natural health products.

• 出版日期2008-11
• 单位吉林农业大学; 中国人民解放军白求恩医务士官学校; 中国人民解放军第二军医大学