Usefulness of a Lung Cancer Rapid Diagnosis Specialist Clinic. Contribution of Ultrasound Bronchoscopy

作者：Sanz Santos Jose^*; Andreo Felipe; Sanchez Dan; Castella Eva; Llatjos Maria; Bechini Jordi; Guasch Ignasi; Lopez De Castro Pedro; Roca Josep; Parra Isidre; Monso Eduard

来源：Archivos de Bronconeumologia, 2010, 46(12): 640-645.

DOI：10.1016/j.arbres.2010.07.005

• Lung cancer
• Endobronchial ultrasound
• Transbronchial needle aspiration
• Time to diagnosis
• Rapid diagnosis unit

Objective: To analyse the results obtained in the diagnosis and staging of lung cancer (LC) by a Lung Cancer Rapid Diagnosis Unit (LC-RDU) in which real-time endobronchial ultrasound-guided transbronchial needle aspiration (RT-EBUS guided-TBNA) is performed as part of the clinical evaluation of the patient prior to treatment.
Method: A four year observational study was conducted on a group of patients evaluated due to suspicion of LC in an LC-RDU. The times and the techniques required for the diagnosis and identifying the level of the disease in the initial staging were recorded.
Results: Out of a total of 678 patients seen in the LC-RDU, the diagnosis in 352 was confirmed in one or more histopathology samples. In 170 patients (48.2%) the diagnosis was made with biopsies and/or cytology samples obtained by fibrobronchoscopy, and RT-EBUS guided-TBNA confirmed the clinical suspicion in 70 patients (19.9%). In the 280 patients with SCLC, 166 RT-EBUS guided-TBNA were performed for staging (59.3%), and in 105 of them the technique only showed local disease (37.5%). Therapeutic surgery was performed on 83 of these patients, and was radical in 73 cases (87.9%).
Conclusion: In half of the patients referred to the LC-RDU due to suspected LC, the diagnosis was confirmed in 75% of cases using endoscopic techniques. RT-EBUS guided-TBNA was the diagnostic technique in 20% of the cases, for staging in more than half of them, and led to reduced waiting times for the diagnosis and starting treatment.

• 出版日期2010-12