Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review

作者：Dhami Sangeeta^*; Nurmatov Ulugbek; Pajno Giovanni Battista; Fernandez Rivas Montserrat; Muraro Antonella; Roberts Graham; Akdis Cezmi; Alvaro Lozano Montserrat; Beyer Kirsten; Bindslev Jensen Carsten; Burks Wesley; du Toit George; Ebisawa Motohiro; Eigenmann Philippe; Knol Edward; Makela Mika; Nadeau Kari Christine; O'Mahony Liam; Papadopoulos Nikolaos; Poulsen Lars; Sackesen Cansin; Sampson Hugh; Santos Alexandra; van Ree Ronald; Timmermans Frans; Sheikh Aziz

来源：Clinical and Translational Allergy, 2016, 6(1): 24.

DOI：10.1186/s13601-016-0113-z

• Allergy
• Allergen immunotherapy
• Food allergy
• Therapy
• Sensitisation

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy.
Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.
Discussion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

• 出版日期2016-7-5