A Drug-Free Zone-Lymph Nodes as a Safe Haven for HIV

作者:Licht Anna; Alter Galit*
来源:Cell Host & Microbe, 2016, 19(3): 275-276.
DOI:10.1016/j.chom.2016.02.018

摘要

Understanding where and how the HIV latent reservoir persists is essential for developing rational HIV cure strategies. In a recent paper in Nature, Lorenzo-Redondo et al. (2016) demonstrate that HIV persists and actively evolves within lymph nodes due to low antiretroviral drug penetration, revealing the need to target these drug-privileged sites.

  • 出版日期2016-3-9
  • 单位MIT