Association of systemic and ocular risk factors with neurosensory retinal detachment in diabetic macular edema: a case-control study

作者：Gupta Aditi; Raman Rajiv; Kulothungan Vaitheeswaran; Sharma Tarun^*

来源：BMC Ophthalmology, 2014, 14(1): 47.

DOI：10.1186/1471-2415-14-47

• Diabetic macular edema
• Neurosensory retinal detachment
• Risk factors
• Blood Pressure

Background: Diabetic macular edema (DME) with neurosensory retinal detachment (NSD) remains an important cause of visual loss in patients with diabetes. The aim of the study was to elucidate the association of systemic and ocular risk factors with NSD in DME.
Methods: In a retrospective case-control study, we reviewed clinical records of all the subjects with DME seen between January 2010 and December 2010. Cases and controls were selected based on optical coherence tomography and stereoscopic biomicroscopy review. NSD was defined as subfoveal fluid accumulation under detached retina with or without overlying foveal thickening. The association between the presence of NSD, blood pressure, lipid status and various other biochemical parameters was evaluated.
Results: Group I (cases) included 37 eyes of 33 patients having DME with NSD and Group II (controls) included 30 eyes of 21 patients having DME without NSD. Patients ranged in age (mean +/- SD) from 50 to 62 years (56.6 +/-6.78) for cases and from 51 to 65 years (58.4+/-7.84) for controls. The duration of diabetes ranged from 4 to 15 year (mean 9.45+/-6.08) among cases and 4 to 14 years (9.7+/-5.12) among controls. Significant risk factors for NSD were high values of systolic and diastolic blood pressure (p = 0.039 and 0.043 respectively).
Conclusion: High systolic and diastolic blood pressures are independent and significant risk factors for NSD in DME.

• 出版日期2014-4-9