Assessing the Role of Counterion in Gold-Catalyzed Dearomatization of Indoles with Allenamides by NMR Studies

作者：Rocchigiani Luca; Jia Minqiang; Bandini Marco^*; Macchioni Alceo

来源：ACS Catalysis, 2015, 5(7): 3911-3915.

DOI：10.1021/acscatal.5b00502

• gold
• NMR spectroscopy
• anion effect
• mechanism
• weak interactions
• homogeneous catalysis

The counterion effect in the gold(I)-catalyzed dearomative condensation of indoles with allenamides is unveiled by means of 1D- and 2D-NMR investigation. The different coordination ability and hydrogen bonding tendency of TFA(-) and OTf- led to specific interactions with the reaction partners dictating the regiodivergent outcome.

• 出版日期2015-7