Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

作者：Gayet Ageron Angele^*; Sednaoui Patrice; Lautenschlager Stephan; Ferry Tristan; Toutous Trellu Laurence; Cavassini Matthias; Yassir Fatima; de Tejada Begona Martinez; Emonet Stephane; Combescure Christophe; Schrenzel Jacques; Perneger Thomas

来源：Emerging Infectious Diseases, 2015, 21(1): 127-129.

DOI：10.3201/eid2101.140790

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.

• 出版日期2015-1