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摘要
A novel approach was developed for the preparation of 4.6-disubstituted-1.2-dihydro-2-oxo-3-pyridinecarboxylic ester in moderate to good yields. This route involves a reaction sequence of Michael addition. transformation to ene-lactam, and aromatization, featuring easily available material, variable substituents, and good functional compatibility.
- 出版日期2004-5-6
- 单位南京大学
