A magnetic resonance imaging nanosensor for Hg (II) based on thymidine-functionalized supermagnetic iron oxide nanoparticles

作者：Yang, Hong^*; Tian, Zhiqing; Wang, Juanjuan; Yang, Shiping

来源：Sensors and Actuators B: Chemical , 2012, 161(1): 429-433.

DOI：10.1016/j.snb.2011.10.055

• MRI nanosensor
• Hg (II)
• Thymidine
• Iron oxide Nanoparticles
• Transverse relaxation rates

A MRI nanosensor for Hg (II) was developed based on superparamagnetic iron oxide nanoparticles (SPIO NPs). The detection mechanism is attributed to Hg (II)-induced nanoassembly of thymidine-functionalized SPIO NPs from a dispersed to an aggregated state with a corresponding decrease in the transverse relaxation time (T-2) of adjacent water protons. Furthermore, an enhancement of transverse relaxation rates (1/T-2) showed the high selectivity for Hg (II) compared with other transition and main group metal ions.

• 出版日期2012-1-3
• 单位上海师范大学