A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients

作者：Chen Li Fen; Lin Ching En; Chou Yu Ching; Mao Wei Chung; Chen Yi Chyan; Tzeng Nian Sheng^*

来源：Neuropsychiatric Disease and Treatment, 2013, 9: 1159-1162.

DOI：10.2147/NDT.S48152

• parasomnia
• somnambulism
• amnesic sleep-related behavior
• sleepwalking
• zolpidem
• zopiclone

Objective: Complex sleep behaviors (CSBs) are classified as %26quot;parasomnias%26quot; in the International Classification of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients in Taiwan. %26lt;br%26gt;Methods: Subjects (N = 1,220) using zolpidem or zopiclone were enrolled from the psychiatric outpatient clinics of a medical center in Taiwan over a 16-month period in 2006-2007. Subjects with zolpidem (N = 1,132) and subjects with zopiclone (N = 88) were analyzed. All subjects completed a questionnaire that included demographic data and complex sleep behaviors after taking hypnotics. %26lt;br%26gt;Results: Among zolpidem and zopiclone users, 3.28% of patients reported incidents of somnambulism or amnesic sleep-related behavior problems. The incidence of CSBs with zolpidem and zopiclone were 3.27%, and 3.41%, respectively, which was significantly lower than other studies in Taiwan. %26lt;br%26gt;Conclusion: These results serve as a reminder for clinicians to make inquiries regarding any unusual performance of parasomnic activities when prescribing zolpidem or zopiclone.

• 出版日期2013