NetCmpt: a network-based tool for calculating the metabolic competition between bacterial species

Kreimer Anat<sup>*</sup>; Doron Faigenboim Adi; Borenstein Elhanan; Freilich Shiri

doi:10.1093/bioinformatics/bts323

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NetCmpt: a network-based tool for calculating the metabolic competition between bacterial species

作者：Kreimer Anat^*; Doron Faigenboim Adi; Borenstein Elhanan; Freilich Shiri

来源：Bioinformatics, 2012, 28(16): 2195-2197.

DOI：10.1093/bioinformatics/bts323

摘要

NetCmpt is a tool for calculating the competitive potential between pairs of bacterial species. The score describes the effective metabolic overlap (EMO) between two species, derived from analyzing the topology of the corresponding metabolic models. NetCmpt is based on the EMO algorithm, developed and validated in previous studies. It takes as input lists of species-specific enzymatic reactions (EC numbers) and generates a matrix of the potential competition scores between all pairwise combinations.