Does intrauterine tobacco exposure increase the pain perception of newborns?

作者：Tekin Mustafa; Yildirim Sule^*; Aylanc Hakan; Kaymaz Nazan; Battal Fatih; Topaloglu Naci; Baser Esra; Binnetoglu Fatih Koksal

来源：Journal of Pain Research, 2016, 9: 319-323.

DOI：10.2147/JPR.S108500

• intrauterine
• newborn
• pain perception
• smoking
• mother

Background: This study aimed to assess whether there was a difference in the pain-perception levels of newborns born to mothers who smoked during pregnancy and newborns born to mothers who were not exposed to active or passive smoking during pregnancy.
Materials and methods: A total of 60 newborns born by normal spontaneous vaginal birth between June 2013 and June 2014 were included in the study: 30 born to mothers who smoked during pregnancy, and 30 born to mothers not exposed to smoking. Mothers or newborns who had taken analgesics or sedative medications in the previous 24 hours, newborns not born at term, and sick newborns were not included in the study. During the routine hepatitis B-vaccination injection given at postnatal 48 hours, the newborns' behavior was monitored and recorded by video camera. The data obtained from the recordings were evaluated according to the Neonatal Pain, Agitation, and Sedation Scale and analyzed with SPSS 20.
Results: The median pain score of the group exposed to tobacco smoke in utero was 8.5, while the median pain score of the unexposed group was 6 (P<0.001).
Conclusion: Exposure to tobacco smoke in utero may increase the pain-perception levels of newborns.

• 出版日期2016