Accumulation of gamma-oryzanol in teleost

作者：Nagasaka Reiko; Kazama Takamitsu; Ushio Hideki^*; Sakamoto Hiroshi; Sakamoto Kenichi; Satoh Shuichi

来源：Fisheries Science, 2011, 77(3): 431-437.

DOI：10.1007/s12562-011-0336-9

• Accumulation
• Gamma-oryzanol
• Hydroxycinnamic acid derivatives
• Physiological function

Japanese people consume crop bran, which contains relatively high amounts of gamma-oryzanol (ORZ), as foodstuffs and food materials. We have recently confirmed that ORZ inhibits NF-kappa B activation, activates peroxisome proliferator-activated receptor gamma (PPAR gamma), and increases plasma adiponectin levels. ORZ is therefore expected to improve lipid and carbohydrate metabolisms and various inflammatory diseases, i.e., metabolic syndrome including type 2 diabetes. ORZ administration also allowed fish, such as rainbow trout, yellowtail, and red sea bream, to accumulate protein through enhancement of lipid and carbohydrate metabolisms. In the present study, we have investigated ORZ accumulation levels in mouse and rainbow trout administered ORZ-containing feed. Although mouse muscle and liver hardly contained ORZ, muscle tissues of every fish species accumulated higher amounts of ORZ. These findings suggest that rainbow trout, red sea bream, and yellowtail accumulate ORZ in muscle.

• 出版日期2011-5