An alternative procedure in the Takai reaction using chromium(III) chloride hexahydrate as a convenient source of chromium(II)

作者：Auge J^*; Boucard V; Gil R; Lubin Germain N; Picard J; Uziel J

来源：Synthetic Communications, 2003, 33(21): 3733-3739.

DOI：10.1081/SCC-120025182

• Takai reaction
• chromium salts
• vinyl iodide

An alternative procedure in the Takai reaction using chromium(III) chloride hexahydrate as the source of Cr(II) was performed. The use of zinc as Cr(III) reducer allowed us to carry out the iodovinylation of aldehydes in 63-99% yields. With the Garner and Dondoni aldehydes, these conditions along with a work-up using 4-t-butyl-pyridine allowed us to improve the yield of the corresponding vinyl iodide compared to the previous procedures.

• 出版日期2003