The Multipartite Mitochondrial Genome of Enteromyxum leei (Myxozoa): Eight Fast-Evolving Megacircles

作者:Yahalomi Dayana; Haddas Sasson Michal; Rubinstein Nimrod D; Feldstein Tamar; Diamant Arik; Huchon Dorothee
来源:Molecular Biology and Evolution, 2017, 34(7): 1551-1556.
DOI:10.1093/molbev/msx072

摘要

Myxozoans are a large group of poorly characterized cnidarian parasites. To gain further insight into their evolution, we sequenced the mitochondrial (mt) genome of Enteromyxum leei and reevaluate the mt genome structure of Kudoa iwatai. Although the typical animal mt genome is a compact, 13-25 kb, circular chromosome, the mt genome of E. leei was found to be fragmented into eight circular chromosomes of similar to 23 kb, making it the largest described animal mt genome. Each chromosome was found to harbor a large noncoding region (similar to 15 kb), nearly identical between chromosomes. The protein coding genes show an unusually high rate of sequence evolution and possess little similarity to their cnidarian homologs. Only five protein coding genes could be identified and no tRNA genes. Surprisingly, themt genome of K. iwatai was also found to be composed of two chromosomes. These observations confirm the remarkable plasticity of myxozoan mt genomes.

  • 出版日期2017-7