Item Reduction, Scoring, and First Validation of the ACCEPTance by the Patients of their Treatment (ACCEPT(C)) Questionnaire

作者：Arnould Benoit; Gilet Helene; Patrick Donald L; Acquadro Catherine^*

来源：Patient-Patient Centered Outcomes Research, 2017, 10(1): 81-92.

DOI：10.1007/s40271-016-0187-7

Objectives The objectives of this study were to finalize, develop the scoring, and explore the psychometric properties of the ACCEPTance by the Patients of their Treatment (ACCEPT(C)) questionnaire, as well as to provide the first elements for its interpretation and guidance for its future use.
Methods ACCEPT(C) was finalized according to reference methods including testing in a pilot study, i.e., a multi-center, observational, longitudinal study conducted in France, in collaboration with a network of pharmacists. Principal component analysis using Varimax rotation was performed. The loadings of items on components in the principal component analysis were used to inform item selection. Validity of the measurement model of ACCEPT(C) was confirmed using Multi-trait/Multi-item Analysis based on item-scale Spearman correlations. Internal consistency reliability of the questionnaire was assessed by determining the Cronbach's alpha coefficient. Linear and logistic regressions were used to identify predictors of general acceptance, and to study predictors of persistence.
Results A total of 189 patients were included. The final version of ACCEPT(C) is composed of 25 items, distributed in seven dimensions providing a comprehensive appraisal of acceptance of long-term medication, with six scores measuring acceptance of treatment specific attributes and one score measuring general treatment acceptance. The measurement pr

• 出版日期2017-2