Memantine and NMDA antagonism for chronic migraine: A potentially novel therapeutic approach?

作者：Spengos Konstantinos^*; Theleritis Christos; Paparrigopoulos Thomas

来源：Headache, 2008, 48(2): 284-286.

• memantine
• NMDA receptor
• chronic migraine
• prophylaxis

We present the case of a woman with chronic migraine who unexpectedly reported full remission of headache after memantine, an NMDA receptor antagonist, was administered for treating concomitant mild cognitive impairment. An underlying dose-dependent effect of memantine on headache symptoms in chronic daily headache and chronic migraine could be assumed.

• 出版日期2008-2