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摘要
A new, cis-selective, approach for the synthesis of bicyclic delta-lactones bearing a fused cyclohex-2-en-1-one moiety is described. The strategy utilizes a cascade reactivity of cyclic 1,3-diketones and 3-arylidenefuran-2(3H)-ones with the butenolidering-opening reaction enabling the construction of the delta-lactone framework. It benefits from broad scope, high enantioselectivity and excellent cis-diastereoselectivity.
- 出版日期2017-9-21
