Nanobiotechnology: quantum dots in bioimaging

作者：Zhong Yong^*; Kaji Noritado; Tokeshi Manabu; Baba Yoshinobu

来源：Expert Review of Proteomics, 2007, 4(4): 565-572.

DOI：10.1586/14789450.4.4-565

• biological application
• modification
• nano
• quantum dot
• synthesis
• toxicity

Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.

• 出版日期2007-8