Mitochondrial DNA in Polish centenarians

作者：Lorenc A; Tonska K; Kabzinska D; Bartnik E^*

来源：Toxicology Mechanisms and Methods, 2004, 14(1-2): 91-95.

DOI：10.1080/15376520490257572

• centenarians
• D-loop
• haplogroups
• mitochondrial DNA

Mitochondrial haplogroups can differ in frequency of occurrence in those who are 100 years old and in the rest of the population. These differences are not universally observed; moreover, they are population-specific. We analyzed the haplogroups in 97 Polish 100-year-olds and compared them with those of more than 145 people who served as controls. No statistically significant differences were observed. In additions, we checked D-loop sequences in 31 controls and in some of the centenarians. Statistically significant differences were found for sites 73 and 152 in the D-loop.

• 出版日期2004-4