New Light on Disordered Ensembles: Ab Initio Structure Determination of One Particle from Scattering Fluctuations of Many Copies

作者:Saldin D K*; Poon H C; Bogan M J; Marchesini S; Shapiro D A; Kirian R A; Weierstall U; Spence J C H
来源:Physical Review Letters, 2011, 106(11): 115501.
DOI:10.1103/PhysRevLett.106.115501

摘要

We report on the first experimental ab initio reconstruction of an image of a single particle from fluctuations in the scattering from an ensemble of copies, randomly oriented about an axis. The method is applicable to identical particles frozen in space or time (as by snapshot diffraction from an x-ray free electron laser). These fluctuations enhance information obtainable from an experiment such as conventional small angle x-ray scattering.

  • 出版日期2011-3-14
  • 单位中国科学院理论物理研究所