Degradation mechanism of magnesium alloy stent under simulated human micro-stress environment

作者：Liu, Dexue^*; Hu, Shiwen; Yin, Xunyan; Liu, Jianjun; Jia, Zhi; Li, Qinglin

来源：Materials Science & Engineering C-Materials for Biological Applications, 2018, 84: 263-270.

DOI：10.1016/j.msec.2017.12.001

• Magnesium alloy stent
• Fluid-structure interaction
• Wall shear stress
• Impedance pump
• Degradation

In this study, a vascular stent made of WE43 magnesium alloy was used as a research object and placed in a special physical simulation device constructed independently. This device provided a platform for the study of the degradation of the stent in a dynamic environment. The simulated body fluid of Hank's buffered salt solution flowing inside it would not only make the stent corroded but also apply cyclic shear stress to it, which get closer to the micro-stress environment in human blood vessels. In addition, by means of computer numerical simulation software, ANSYS Fluent 15.0, the fluid-structure interaction (FSI) model was established to simulate the wall shear stress (WSS) exerted by the flowing blood on stent in the blood vessel. Combined with the results of numerical simulation and physical simulation experiments, the degradation mechanism of magnesium alloy sent in an environment similar to the human blood vessels was studied.

• 出版日期2018-3-1
• 单位兰州理工大学