Anti-hyperglycemic activity of Trichosanthes tricuspidata root extract

作者:Kulandaivel Srinivasan*; Bajpai Pawan; Sivakumar Thangavel
来源:Bangladesh Journal of Pharmacology, 2013, 8(3): 305-310.
DOI:10.3329/bjp.v8i3.15584

摘要

To evaluate the anti-diabetic activity of ethanolic extract of Trichosanthes tricuspidata root in alloxan induced diabetic rats and to perform the phytochemical screening. The extraction, preliminary phytochemical screening, antidiabetic activity in alloxan induced diabetic rats by oral administration of extract (200 and 400 mg/kg b.w.), the blood glucose level and biochemical parameters like cholesterol, triglyceride, serum protein, SGPT, SGOT, and ALP were estimated. Phytochemical studies shows the presence of carbohydrates, proteins, glycosides and terpenoids and the ethanolic extract of T. tricuspidata root significantly lowered the blood sugar level. The above findings justified the traditional claim of anti-diabetic activity in this plant.

  • 出版日期2013