Development and validation of a quantitative method to assess pedicle screw loosening in posterior spine instrumentation on plain radiographs

作者：Aghayev Emin^*; Zullig Nicolas; Diel Peter; Dietrich Daniel; Benneker Lorin M

来源：European Spine Journal, 2014, 23(3): 689-694.

DOI：10.1007/s00586-013-3080-2

• Pedicle screw loosening
• Pedicle screw complication
• Pedicle screw angle
• Pedicle screw position
• Posterior spine instrumentation

Currently, the diagnosis of pedicle screw (PS) loosening is based on a subjectively assessed halo sign, that is, a radiolucent line around the implant wider than 1 mm in plain radiographs. We aimed at development and validation of a quantitative method to diagnose PS loosening on radiographs.
Between 11/2004 and 1/2010 36 consecutive patients treated with thoraco-lumbar spine fusion with PS instrumentation without PS loosening were compared with 37 other patients who developed a clinically manifesting PS loosening. Three different angles were measured and compared regarding their capability to discriminate the loosened PS over the postoperative course. The inter-observer invariance was tested and a receiver operating characteristics curve analysis was performed.
The angle measured between the PS axis and the cranial endplate was significantly different between the early and all later postoperative images. The Spearman correlation coefficient for the measurements of two observers at each postoperative time point ranged between 0.89 at 2 weeks to 0.94 at 2 months and 1 year postoperative. The angle change of 1.9A degrees between immediate postoperative and 6-month postoperative was 75 % sensitive and 89 % specific for the identification of loosened screws (AUC = 0.82).
The angle between the PS axis and the cranial endplate showed good ability to change in PS loosening. A change of this angle of at least 2A degrees had a relatively high sensitivity and specificity to diagnose screw loosening.

• 出版日期2014-3