Multiobjective guided priors improve the accuracy of near-infrared spectral tomography for breast imaging

作者：Feng, Jinchao^*; Jiang, Shudong; Xu, Junqing; Zhao, Yan; Pogue, Brian W.; Paulsen, Keith D.^*

来源：Journal of Biomedical Optics, 2016, 21(9): 090506.

DOI：10.1117/1.JBO.21.9.090506

• MRI-guided optical image reconstruction
• near-infrared spectral tomography
• breast imaging

An image reconstruction regularization approach for magnetic resonance imaging-guided near-infrared spectral tomography has been developed to improve quantification of total hemoglobin (HbT) and water. By combining prior information from dynamic contrast enhanced (DCE) and diffusion weighted (DW) MR images, the absolute bias errors of HbT and water in the tumor were reduced by 22% and 18%, 21% and 6%, and 10% and 11%, compared to that in the no-prior, DCE- or DW-guided reconstructed images in three-dimensional simulations, respectively. In addition, the apparent contrast values of HbT and water were increased in patient image reconstruction from 1.4 and 1.4 (DCE) or 1.8 and 1.4 (DW) to 4.6 and 1.6.

• 出版日期2016-9
• 单位北京工业大学