Assessment of mean respiratory rate from ECG recordings for risk stratification after myocardial infarction

作者:Sinnecker Daniel; Dommasch Michael; Barthel Petra; Mueller Alexander; Dirschinger Ralf J; Hapfelmeier Alexander; Huster Katharina M; Laugwitz Karl Ludwig; Malik Marek*; Schmidt Georg
来源:Journal of Electrocardiology, 2014, 47(5): 700-704.
DOI:10.1016/j.jelectrocard.2014.04.021

摘要

Background: We recently reported that nocturnal respiratory rate (NRR) predicts non-sudden cardiac death in survivors of myocardial infarction (MI). Here, we present the details of the technique deriving NRR from ECG recordings. Methods: Continuous ECG and respiratory chest excursions were simultaneously recorded in 941 MI survivors who were followed-up for 5-years. Mean respiratory rate was derived from the ECG based on RR intervals, QRS amplitudes, and QRS vectors and compared to chest belt measurements. NRR was calculated from Holter-ECGs accordingly using the same ECG processing. Results: Directly-measured and ECG-derived respiratory rates were in good agreement. Areas under the ROC curve for 10-min-ECG- and Holter-derived respiratory rate were well in the confidence intervals of that of the chest belt measurement. The optimum dichotomy of NRR for the prediction of mortality was >= 18.6 breaths per minute. Conclusions: The mean respiratory rate can be precisely derived from continuous ECGs.