Usefulness of two-point Dixon fat-water separation technique in gadoxetic acid-enhanced liver magnetic resonance imaging

作者：Ding Ying; Rao Sheng Xiang^*; Chen Cai Zhong; Li Ren Chen; Zeng Meng Su

来源：World Journal of Gastroenterology, 2015, 21(16): 5017-5022.

DOI：10.3748/wjg.v21.i16.5017

• Dixon-volumetric interpolated breath-hold examination
• Fat saturation-volumetric interpolated breath-hold examination
• Gadoxetic acid
• Volumetric interpolated breath-hold examination
• Magnetic resonance imaging

AIM: To compare differences between volumetric interpolated breath-hold examination (VIBE) using two-point Dixon fat-water separation (Dixon-VIBE) and chemically selective fat saturation (FS-VIBE) with magnetic resonance imaging examination.
METHODS: Forty-nine patients were included, who were scanned with two VIBE sequences (Dixon-VIBE and FS-VIBE) in hepatobiliary phase after gadoxetic acid administration. Subjective evaluations including sharpness of tumor, sharpness of vessels, strength and homogeneity of fat suppression, and artifacts that were scored using a 4-point scale. The liver-to-lesion contrast was also calculated and compared.
RESULTS: Dixon-VIBE with water reconstruction had significantly higher subjective scores than FS-VIBE in strength and homogeneity of fat suppression (< 0.0001) but lower scores in sharpness of tumor (P < 0.0001), sharpness of vessels (P = 0.0001), and artifacts (P = 0.034). The liver-to-lesion contrast on Dixon-VIBE images was significantly lower than that on FS-VIBE (16.6% +/- 9.4% vs 23.9% +/- 12.1%, P = 0.0001).
CONCLUSION: Dixon-VIBE provides stronger and more homogenous fat suppression than FS-VIBE, while has lower clarity of focal liver lesions in hepatobiliary phase after gadoxetic acid administration.

• 出版日期2015-4-28
• 单位河北医科大学; 复旦大学