A severe case of esophageal ulcer causing a tight stricture despite long-term D-penicillamine treatment

作者：Yapali Suna^*; Turan Ilker; Ozutemiz Omer; Tekesin Oktay

来源：WIENER KLINISCHE WOCHENSCHRIFT, 2014, 126(23-24): 789-791.

DOI：10.1007/s00508-014-0610-9

• D-penicillamine
• Esophageal ulcer
• Esophageal stricture
• Peptic stricture
• Balloon dilation

D-penicillamine has long been used in the management of rheumatic diseases due to the effects on inhibition of collagen synthesis. Herein, we report a severe case of esophageal ulcer causing a tight stricture extending through the distal esophagus despite the long-term D-penicillamine treatment in a patient with Wilson%26apos;s disease. D-penicillamine would theoretically be expected to contribute to the healing of an esophageal ulcer. However, the drug failed to have a favorable outcome, which is notable and worth reporting.

• 出版日期2014-12