A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins

作者:Ollivier N; Desmet R; Drobecq H; Blanpain A; Boll E; Leclercq B; Mougel A; Vicogne J; Melnyk O
来源:Chemical Science, 2017, 8(8): 5362-5370.
DOI:10.1039/c7sc01912b

摘要

We show that the combination of solid phase and solution ligation techniques facilitates the production of a challenging and biologically active protein made of 180 amino acids.

  • 出版日期2017-8