Decrease in fMRI brain activation during working memory performed after sleeping under 10 lux light

作者：Kang Seung Gul; Yoon Ho Kyoung; Cho Chul Hyun; Kwon Soonwook; Kang June; Park Young Min; Lee Eunil; Kim Leen; Lee Heon Jeong^*

来源：Scientific Reports, 2016, 6(1): 36731.

DOI：10.1038/srep36731

The aim of this study was to investigate the effect of exposure to dim light at night (dLAN) when sleeping on functional brain activation during a working-memory tasks. We conducted the brain functional magnetic resonance imaging (fMRI) analysis on 20 healthy male subjects. All participants slept in a polysomnography laboratory without light exposure on the first and second nights and under a dim-light condition of either 5 or 10 lux on the third night. The fMRI scanning was conducted during n-back tasks after second and third nights. Statistical parametric maps revealed less activation in the right inferior frontal gyrus (IFG) after exposure to 10-lux light. The brain activity in the right and left IFG areas decreased more during the 2-back task than during the 1- or 0-back task in the 10-lux group. The exposure to 5-lux light had no significant effect on brain activities. The exposure to dLAN might influence the brain function which is related to the cognition.

• 出版日期2016-11-9