A Simple, Efficient Green Protocol for the Synthesis of beta-Enaminone and Enamino Ester Derivatives by Using Onion Extract as Green Catalyst

作者：Prabakaran Kaliyan; Sivakumar Matam; Perumal Muthu Seenivasa^*

来源：ChemistrySelect, 2017, 2(8): 2363-2372.

DOI：10.1002/slct.201601515

• Amine
• 1,3-Dicarbonyl
• beta-Enaminone
• Excellent yields
• Onion extract as green catalyst

We have developed an environmental friendly and highly efficient method for onion extract catalyzed enamination of 1,3-dicarbonyl compounds and primary amines. This method is applicable to a wide range of aromatic/aliphatic/heterocyclic amines with active methylene compounds, and affords the -enaminone and enamino ester derivatives in good to excellent yields (up to 97%) in an eco-friendly solvent ethanol at room temperature. The use of onion extract makes the process environmentally benign.

• 出版日期2017-3-13