Mitotic activity of a new phytotherapeutic product with a trade name of "Ganomix"

作者：Kuras Mieczyslaw^*; Gulewicz Krzysztof; Bemowska Kalabun Olga; Wierzbicka Malgorzata

来源：Caryologia, 2016, 69(4): 295-302.

DOI：10.1080/00087114.2016.1188358

• Ganomix
• Uncaria tomentosa
• Ganoderma lucidum
• mitotic activity

Water extracts of Uncaria tomentosa (Vilcacora) bark and Ganoderma lucidum (Reishi) spores that are rich in biologically active compounds, are increasingly widely used in prevention and treatment of many serious medical conditions. They are considered an important treatment option, complementary to phytotherapeutics and synthetic medicines. A new formulation with a trade name of Ganomix was developed based on these two components. The aim of this study was to determine mitotic activity of Ganomix and to compare the activity of Ganomix with the activity of its individual components. The biological activity was assessed using the following plant tests: Allium test (Levan test) and Phytotoxkit biotest. In addition, the chemical composition of selected components was analyzed. Water extracts of Vilcacora bark and Reishi spores, as well as their combination in Ganomix, exhibited varying biological activities. The Vilcacora bark extracts had inhibitory effects at the great majority of concentrations tested, while Reishi spore extracts were mainly stimulatory at the same range of concentrations. However, Ganomix extract showed an intermediate effect compared with Vilcacora bark and Reishi spore extracts. The promising results of these investigations give hope for the effective use of Ganomix in prevention and therapy of different sicknesses.

• 出版日期2016