A Custody Battle for the Mind: Evidence for Extensive Imprinting in the Brain

作者:Tollkuhn Jessica; Xu Xiaohong; Shah Nirao M*
来源:Neuron, 2010, 67(3): 359-362.
DOI:10.1016/j.neuron.2010.07.026

摘要

Relatively few genes (similar to 100) have previously been shown to be imprinted such that their expression in progeny derives from either the maternal or paternal copy. Two recent studies by Gregg et al. (2010a, 2010b) in Science expand this list by an order of magnitude, revealing complex patterns of parent-of-origin bias in gene expression in the brain that are developmentally and regionally restricted, and in many cases, sexually dimorphic.

  • 出版日期2010-8-12