Anti-Escherichia coli activity of extracts from Schinus terebinthifolius fruits and leaves

作者:da Silva Jessica H S*; Simas Naomi K; Alviano Celuta S; Alviano Daniela S; Ventura Jose A; de Lima Eliandro J; Seabra Sergio H; Kuster Ricardo M
来源:Natural Product Research, 2018, 32(11): 1365-1368.
DOI:10.1080/14786419.2017.1344657

摘要

Ethanol extracts obtained from Schinus terebinthifolius Raddi fruits and leaves were active against Escherichia coli with MIC of 78gmL(-1) for both extracts. Phytochemical analyses revealed a major presence of phenolic acids, tannins, fatty acids and acid triterpenes in the leaves and phenolic acids, fatty acids, acid triterpenes and biflavonoids in the fruits. Major compounds isolated from the plant, such as the acid triterpene schinol, the phenolic acid derivative ethyl gallate and the biflavonoids agathisflavone and tetrahydroamentoflavone, showed very little activity against E. coli. Bioautography of the ethanol extracts on silica gel plate showed inhibition zones for E. coli. They were removed from the plate and the compounds identified as a mixture of myristic, pentadecanoic, palmitic, heptadecanoic, stearic, nonadecanoic, eicosanoic, heneicosanoic and behenic fatty acids.
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  • 出版日期2018