Allergen immunotherapy for insect venom allergy: protocol for a systematic review

作者：Dhami Sangeeta^*; Nurmatov Ulugbek; Varga Eva Maria; Sturm Gunter; Muraro Antonella; Akdis Cezmi A; Antolin Amerigo Dario; Bilo M Beatrice; Bokanovic Danijela; Calderon Moises A; Cichocka Jarosz Ewa; Oude Elberink Joanna N G; Gawlik Radoslaw; Jakob Thilo; Kosnik Mitja; Lange Joanna; Mingomataj Ervin; Mitsias Dimitris I; Mo**ech Holger; Pfaar Oliver; Pitsios Constantinos; Pravettoni Valerio; Roberts Graham; Rueeff Franziska; Sin Betul Ayse; Sheikh Aziz

来源：Clinical and Translational Allergy, 2016, 6(1): UNSP 6.

DOI：10.1186/s13601-016-0095-x

• Allergy
• Insect sting
• Hymenoptera venom allergy
• Insect venom allergy
• Allergen immunotherapy
• Systemic sting reaction

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy.
Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.
Discussion: The findings from this review will be used to inform the development of recomendations for EAACI's Guidelines on AIT.

• 出版日期2016-2-16