摘要

In the present paper a study on the possibility of obtaining Ag-loaded hydroxyapatite coatings on porous polyurethane surfaces by biomimetic deposition is reported. To achieve the formation of hydroxyapatite deposition on the surface of polyurethane and to incorporate the silver in the apatite layer, a supersaturated calcification solution containing silver ions was used. The samples were investigated by means of scanning electron microscopy (SEM) coupled with X-ray analysis (EDX), X-ray diffraction (XRD) and Fourier-transform infrared transmission spectroscopy (FT-IR). The hydroxyapatite/Ag coatings were evaluated for their antibacterial activity against Staphylococcus aureus and Escherichia coli. The results obtained by SEM-EDX, XRD and FT-IR investigations revealed that porous polyurethane/hydroxyapatite scaffolds were formed, and the silver was incorporated into the apatite layer. The obtained data were also indicative of good antibacterial properties of the materials thus prepared.

  • 出版日期2013-3