Novel therapeutic strategies targeting ASK1 in NASH

作者：Schuster Susanne; Feldstein Ariel E^*

来源：Nature Reviews Gastroenterology & Hepatology, 2017, 14(6): 329-330.

DOI：10.1038/nrgastro.2017.42

Currently, no pharmacological therapies are approved for the treatment of NASH. A new study now identifies CASP8 and FADD-like apoptosis regulator (CFLAR) as a novel suppressor of NASH and its associated disorders in a process dependent on the activation of apoptosis signal-regulating kinase 1 (ASK1).

• 出版日期2017-6