Assessment of a Novel Vaccine Against Rabbit Hemorrhagic Disease Virus in Young Rabbits

作者：Pacho Sonsoles; Dahdouh Elias; Merino Javier; Suarez Monica^*

来源：Viral Immunology, 2016, 29(10): 583-585.

DOI：10.1089/vim.2016.0093

• disease
• immunization
• rabbits
• RHDVb
• vaccination

Rabbit hemorrhagic disease virus (RHDVb) is the new variant of the classical RHDV, a virulent pathogen responsible for an acute disease in young rabbits. The virus invades internal organs, especially the liver, spleen, kidneys, and gut; prevents coagulation; and causes liver necrosis. This eventually leads to quick death of the animal because of hemorrhage. In this study, we evaluated the effects of a new vaccine against RHDVb in rabbits at a young age, after experimental infection using four different viral isolates. Our findings show that the vaccine had a protective effect with survival rates reaching 80-100% against the different isolates. These results suggest that this vaccine, when applied to young animals, is an effective tool to protect against the disease caused by RHDVb in rabbitries.

• 出版日期2016-12