Allgrove's syndrome in patients with a previous history of hypertrophic pyloric stenosis. A case study and literature review

作者：Lahmidani N; El Yousfi M; Benajah D; El Abkari M; Ibrahimi A

来源：Acta Endoscopica, 2012, 42(2): 52-53.

DOI：10.1007/s10190-011-0225-1

• Triple-A syndrome
• Allgrove's syndrome
• Congenital alacrima
• Adrenal insufficiency
• Achalasia

Allgrove's syndrome is a rare, recessive autosomal condition, associated with alacrima, achalasia and adrenal insufficiency. It is also often associated with neurological disorders. Recently, mutation of the AAAS candidate gene on chromosome 12q13 has been identified.We are reporting the observation made on a young patient, operated on at the age of one for hypertrophic pyloric stenosis, who twenty years later was diagnosed with Allgrove's syndrome during a check-up for achalasia. Triple-A syndrome should be suspected in all young patients presenting with achalasia and adrenal insufficiency.

• 出版日期2012-3