A Novel Reassortant H2N3 Influenza Virus Isolated from China

作者：Li Xiao Dan; Zou Shu Mei; Zhang Ye; Bai Tian; Gao Rong Bao; Zhang Xin; Wu Jie; Shu Yue Long^*

来源：Biomedical and Environmental Sciences, 2014, 27(4): 240-249.

DOI：10.3967/bes2014.047

• Avian influenza
• Gene analysis
• H2N3

Objective To analyze the genetic composition of a novel H2N3 virus isolate identified from a duck cage swab in a live poultry marlet (LPM) in 2009 Guangdong province in China. @@@ Methods PCR-positive specimens were inoculated into embryonated chicken eggs and subtyped by conventional RT-PCR. All segments of the virus A/environment/Guangdong/2/2009 were sequenced, and phylogenetic trees were constructed and analyzed. @@@ Results The genes of this virus belong to Eurasian-lineage avian viruses. The virus is a reassortant with the HA gene from an H2N2 virus annd the NA gene from an H5N3 virus. The PB1, PB2, and NP genes were from an H4N6 virus, the PA was from an H3N8 virus, the M gene was from an H1N3 virus, and the NS gene was from an H10N6 virus. @@@ conclusion A novel avian-orgin reassortant H2N3 influenza virus was detected in a live poultry market. Its potential impacts and evolution should be closely monitored.

• 出版日期2014-4
• 单位中国疾病预防控制中心; 广东省疾病预防控制中心