A population study of binocular function

作者：Bosten J M^*; Goodbourn P T; Lawrance Owen A J; Bargary G; Hogg R E; Mollon J D

来源：Vision Research, 2015, 110: 34-50.

DOI：10.1016/j.visres.2015.02.017

• Stereo acuity
• Stereopsis
• Dichoptic masking
• Binocular rivalry
• GWAS
• Individual differences

As part of a genome-wide association study (GWAS) of perceptual traits in healthy adults, we measured stereo acuity, the duration of alternative percepts in binocular rivalry and the extent of dichoptic masking in 1060 participants. We present the distributions of the measures, the correlations between measures, and their relationships to other psychophysical traits. We report sex differences, and correlations with age, interpupillary distance, eye dominance, phorias, visual acuity and personality. The GWAS, using data from 988 participants, yielded one genetic association that passed a permutation test for significance: The variant rs1022907 in the gene VTI1A was associated with self-reported ability to see autostereograms. We list a number of other suggestive genetic associations (p < 10(-5)).

• 出版日期2015-5