科研之友
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摘要
A novel sensor is developed for the detection of amobarbital in urines, which is based on an electropolymerized molecularly imprinted polymer (MIP) on the surface of the CuO nanoparticles modified glassy carbon electrode. The optimums film formed conditions and experimental conditions were explored. The surface feature and performance of the modified electrode were characterized by scanning electron microscope (SEM), cyclic voltammetry(CV) and electrochemical impedance spectroscopy(EIS). The results of electrochemical measurements indicated that CuO nanoparticles had good sensitization effected for the molecularly imprinted sensor and it exhibits good sensitivity and selectivity to the template molecule amobarbital. Under the optimal conditions, the relative redox peak currents of hexacyanoferrate were linear. The concentration of amobarbital ranged from 1.0x10(-7) to 1.4x10(-4) mol/L, with a linear correlation coefficient of 0.9966. The detection limit was 2.1x10(-9) mol/L(S/N =3). The prepared sensor was applied to the determination of amobarbital in urine samples with recovery ranging from 94.00% to 104.67%.
