科研之友
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摘要
Posterior spinal reconstruction with rods and pedicle screws has been widely used to corrects coliosis and other forms of degenerative spinal deformities. However, insertion of pedicle screwsis often clinically challenging, particularlyin patients with severe deformity. Bioelectrical impedance analysis is a technique that exploits the electrical properties of biological organs and tissues to indicate their compositions. Bioelectrical impedance measurement is non-invasive, simple, with adequate repeatability, and at a relatively low cost. In our study, we designed a bioelectrical impedance pedicle probe and use it to determine the bioelectrical impedance values in vitro and in vivo of different tissues relevant to pedicle screw insertion. We measured the bioelectrical impedance of different tissues relevant to pedicle screw placement in vitro and in vivo and explored the use of a prototype bioelectrical impedance pedicle probein guiding pedicle screw placement during spine surgery in animals. These data suggested that this novel bioelectrical impedance pedicle probe may be a new technique that has potential to offer accurate and safe placement of pedicle screws in spine surgery.
- 出版日期2018
- 单位香港中文大学; 北京积水潭医院; 清华大学; 北京协和医学院; 中国医学科学院北京协和医院; 北京大学
