Aerobic oxidative dehydrogenation of N-heterocycles catalyzed by cobalt porphyrin

作者：Zhou, Weiyou; Chen, Dongwei; Sun, Fu'an; Qian, Junfeng; He, Mingyang^*; Chen, Qun

来源：Tetrahedron Letters, 2018, 59(10): 949-953.

DOI：10.1016/j.tetlet.2018.01.094

• N-Heterocycles
• Cobalt porphyrin
• Oxidative dehydrogenation
• No additive

An efficient catalytic procedure has been developed for the aerobic oxidative dehydrogenation of N-heterocycles by cobalt porphyrin in the absence of any additives. The catalytic system could tolerate various 1,2,3,4-tetrahydroquinoline derivatives and some other N-heterocycles. The corresponding N-heteroaromatics could be obtained in 59-86% yields. The mechanism investigation suggested that the aerobic oxidative dehydrogenation might proceed with imine intermediate through radical paths.

• 出版日期2018-3-7
• 单位常州大学