Neoline from Aconitum flavum Hand

作者：Liu, Wei; Gou, Xiong-Jun; Song, Qin; Chen, Feng-Zheng

来源：Acta Crystallographica Section E-Structure Reports Online, 2011, 67: O1435-U876.

DOI：10.1107/S1600536811015170

The title compound, C(24)H(39)NO(6) [systematic name: (1 alpha,6 alpha,14 alpha,16 beta)-N-ethyl-6,16-dimethoxy-4-methoxymethylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The molecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings. Both five-membered rings adopt envelope conformations. Two six-membered rings adopt chair conformations, whereas the other two adopt boat conformations. Intramolecular O-H...O and O-H...N and intermolecular O-H...O hydrogen bonds are present in the structure. In the crystal, one methyl group is disordered over two sites with an occupancy ratio of 0.70 (3):0.30 (3).

• 出版日期2011-6
• 单位成都大学