Asymmetric Pauson-Khand-type reactions of 1,6-enynes using formaldehyde as a carbonyl source by cooperative dual rhodium catalysis

作者：Furusawa Takuma; Morimoto Tsumoru^*; Ikeda Keiichi; Tanimoto Hiroki; Nishiyama Yasuhiro; Kakiuchi Kiyomi; Jeong Nakcheol

来源：Tetrahedron, 2015, 71(5): 875-881.

DOI：10.1016/j.tet.2014.12.038

• Asymmetric Pauson-Khand reaction
• Decarbonylation
• Formaldehyde
• Enyne
• Dual catalysis

A dual neutral-cationic rhodium(I)-catalyzed Pauson-Khand-type reaction using formaldehyde as a carbonyl source is described. The simultaneous use of neutral rhodium(I) and cationic rhodium(l) complexes is required for efficient cooperative catalysis, which involves the neutral rhodium(l)-catalyzed decarbonylation of formaldehyde and the cationic rhodium(I)-catalyzed cyclocarbonylation of 1,6-enynes using the resulting carbonyl moiety.

• 出版日期2015-2-4